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Physician Assistants   Tags: pa, physician assistant  

Last Updated: Aug 31, 2017 URL: Print Guide RSS Updates

PYAS 6551- Research Assignment-Critical Appraisal Tools Print Page

Analysis Resources

Clinical Epidemiology: The Essentials
Funding for this book is provided by TRIP, LSU Health Shreveport’s Quality Enhancement Plan


Understanding Research Designs


EBM Pyramid


Searching for Study Type

Identify the question type in order to identify the best type of study to answer the clinical question.  This will assist in searching PubMed to find the most specific information.


Question Type

Study Design

Search To Use

Therapy:  how to select treatments that do more good than harm

RCT>cohort > case control > case series

sensitive/broad   99%/70%

 specific/narrow   93%/97%

Diagnosis and screening:  how to select and interpret tests

Prospective, blind comparison to gold standard

sensitive/broad   98%/74%

specific/narrow   64%/98%

Etiology:  what factors led to the development of an illness or condition

RCT>cohort > case control > case series

sensitive/broad   93%/63%

specific/narrow   51%/95%

Prognosis:  how to anticipate the patient’s likely course

Cohort > case control > case series

sensitive/broad   90%/80%

specific/narrow   52%/94%


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